NC BERD Seminar: Machine Learning for Precise Diagnostics and Therapeutics

The Carter Lab develops and applies computational approaches to aid the interpretation of genetic variation and to advance precision cancer medicine. A major focus of the lab is on joint analysis of tumor and inherited genomes to uncover the role of genetic background in shaping cancer risk, somatic tumor evolution and therapeutic response. Her recent work investigates how the inherited immune system affects tumor genome evolution and the characteristics of the tumor immune microenvironment to identify opportunities and barriers for immunotherapy.

Speaker:
Hannah Carter, MEng, PhD
Associate Professor
Department of Medicine, Division of Genomics and Precision Medicine
University of California at San Diego

This event is sponsored by Duke University Departments of Computational Biology and Bioinformatics (CBB) and Biostatistics and Bioinformatics, the Duke Center for Genomic and Computational Biology (GCB), the Precision Genomics Collaboratory, and the Duke University School of Medicine. It is being cross-promoted by the North Carolina BERD Consortium (Duke University School of Medicine, University of North Carolina-Chapel Hill, and Wake Forest School of Medicine).

Virtual Public Meeting on Good Clinical Practice: Considerations for Clinical Trials with Decentralized or Pragmatic Features

The U.S. Food and Drug Administration, in collaboration with the Reagan-Udall Foundation for the FDA, will convene international experts in the conduct of clinical trials with pragmatic or decentralized features. Clinical trials with streamlined protocols that are embedded in existing health care infrastructure (often referred to as pragmatic trials), and trials with decentralized processes have the potential to generate evidence more efficiently while minimizing the burden on participants.

Representatives from the research community will share their experiences conducting clinical trials with pragmatic or decentralized features. The two-day virtual public meeting will include presentations and moderated discussion to provide a better understanding of the opportunities and challenges of conducting trials with these innovative design features. Learnings from the meetings will inform the development of responsive policies and guidelines that encourage innovation, while protecting participants and safeguarding the reliability of trial results.

You can contribute to the discussion. Share your questions when you register, and as many as possible will be included in the discussion.

The meeting agenda is available and will be updated as more information is provided. Full recordings of both sessions will be available after the meeting along with the complete slide deck and transcript.

Register

Virtual Public Meeting on Good Clinical Practice: Considerations for Clinical Trials with Decentralized or Pragmatic Features

The U.S. Food and Drug Administration, in collaboration with the Reagan-Udall Foundation for the FDA, will convene international experts in the conduct of clinical trials with pragmatic or decentralized features. Clinical trials with streamlined protocols that are embedded in existing health care infrastructure (often referred to as pragmatic trials), and trials with decentralized processes have the potential to generate evidence more efficiently while minimizing the burden on participants.

Representatives from the research community will share their experiences conducting clinical trials with pragmatic or decentralized features. The two-day virtual public meeting will include presentations and moderated discussion to provide a better understanding of the opportunities and challenges of conducting trials with these innovative design features. Learnings from the meetings will inform the development of responsive policies and guidelines that encourage innovation, while protecting participants and safeguarding the reliability of trial results.

You can contribute to the discussion. Share your questions when you register, and as many as possible will be included in the discussion.

The meeting agenda is available and will be updated as more information is provided. Full recordings of both sessions will be available after the meeting along with the complete slide deck and transcript.

Register

AAP-SPROUT Tele-inpatient ECHO: Virtual inpatient subspecialty consults

The American Academy of Pediatrics is recruiting hospitalists, pediatricians, and other health professionals to be a part of the SPROUT (Supporting Pediatric Research on Outcomes and Utilization of Telehealth) Tele-inpatient ECHO (Extension for Community Healthcare Outcomes). This ECHO, in partnership with the SPROUT-CTSA Network, will serve as a forum for increasing knowledge, skills, and self-efficacy regarding effective strategies and best practices related to telehealth in the hospital setting.

Project ECHO® is an innovative hub and spoke program, designed to create knowledge networks by connecting health care providers with an expert team through a tele-mentoring program using brief lectures and case‐based presentations. This ECHO, in partnership with the SPROUT-CTSA Network, will serve as a forum for increasing knowledge, skills, and self-efficacy regarding effective strategies and best practices related to telehealth in the hospital setting.

The AAP-SPROUT Tele-inpatient ECHO will meet monthly September 2023 through February 2024 at at 12 PM ET on the following dates: September 13, October 11, November 15, December 13, January 10, and February 14. Participants are eligible to claim CME/MOC 2 credits.

September 13, 2023 topic: Virtual inpatient subspecialty consults | Presenter: Christina Olson, MD | Facilitator: Jordan Vaughn, MD, FAAP

Questions? Email Robinn Yu, Program Manager of ECHO Initiatives, This email address is being protected from spambots. You need JavaScript enabled to view it.

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This project was supported in part by NIH/ NCATS SPROUT-CTSA Collaborative Telehealth Network Grant Number U01TR002626. The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH.

The Interdisciplinary Nutrition Sciences Symposium (INSS) is an annual translational nutrition science conference. The theme for 2023 is Obesity and the Brain Across the Life Course.

This conference will address the critical need to establish rigorous interdisciplinary and translational approaches in the context of nutrition and obesity to effectively prevent and treat a variety of physiological outcomes as they relate to aging and the brain.

Scientific themes:

• Epidemiology of Aging, Obesity, and the Brain
• Gut-Brain Axis in Obesity and Aging
• The Brain-Inflammation Connection
• How Can Transitional Geroscience Impact the Aging Brain
• Obesity, Cognitive Function, and Interventions

Learn more at the INSS conference website.

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Strategies To Ensure Completion Of The Doctoral Dissertation

The dissertation is one of the most pivotal components of doctoral programs in higher education. Yet, this is the obstacle that doctoral students have the most difficulty overcoming. This workshop will present proven strategies for mapping out a dissertation completion plan in any discipline. Workshop participants will learn how to develop relational success with the dissertation chair and committee, identify and delimit the dissertation topic, undertake a disciplined approach to the review of literature and become familiar with the essential chapter development of the dissertation. The workshop program will share specific academic practices that successful doctoral students employed to complete their dissertations on time.

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This interactive online workshop will focus on semi-structured interviewing, a data collection method used in qualitative research. Participants will have the opportunity to practice developing interview questions and using interviewing skills.

Topics:

• Basics of semi-structured interviews
• Development of interview questions and probes
• Interviewing skills
• Considerations for conducting virtual interviews.

Presenters:
MaryBeth Grewe, MPH
Engagement and Qualitative Research Specialist
NC TraCS Institute

Simone Frank, MPH
Community Engagement and Outreach Specialist
NC TraCS Institute

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AI Health Virtual Seminar: Real-world Applications of AI Chatbots with ChatGPT

Join Duke AI Health for an engaging presentation on the transformative power of Generative Artificial Intelligence (AI) in the form of Chatbots. Designed for individuals with little to no experience in using AI Chatbots, this event aims to share valuable insights with a broad community, both at Duke and beyond. This talk will focus on leveraging ChatGPT, a cutting-edge language model developed by OpenAI, to automate mundane tasks.

Stephen Toback, Assistant Director of Academic Media Production and Engineering will showcase real-world applications of ChatGPT, including prompt engineering and refinement, practical implications, and security and privacy considerations. Don't miss this opportunity to learn about the fascinating world of AI Chatbots and connect with a vibrant community of innovators, researchers, and enthusiasts. And yes, this description was drafted by ChatGPT!

Speaker:
Stephen Toback
Media Architect/Senior Producer
Academic Media Engineering & Production, Duke Office of Information Technology

Host:
Shelley Rusincovitch, MMCi
Managing Director, Duke AI Health

This event is sponsored by Duke AI Health; the Duke University Departments of Biostatistics & Bioinformatics, Computer Science, and Electrical and Computer Engineering; the Duke Center for Computational Thinking; CTSI CREDO; the Duke University Office of Information Technology (OIT); and the Pratt School of Engineering. It is being cross-promoted by the North Carolina BERD Consortium (Duke University School of Medicine, University of North Carolina-Chapel Hill, and Wake Forest School of Medicine).

The Interdisciplinary Nutrition Sciences Symposium (INSS) is an annual translational nutrition science conference. The theme for 2023 is Obesity and the Brain Across the Life Course.

This conference will address the critical need to establish rigorous interdisciplinary and translational approaches in the context of nutrition and obesity to effectively prevent and treat a variety of physiological outcomes as they relate to aging and the brain.

Scientific themes:

• Epidemiology of Aging, Obesity, and the Brain
• Gut-Brain Axis in Obesity and Aging
• The Brain-Inflammation Connection
• How Can Transitional Geroscience Impact the Aging Brain
• Obesity, Cognitive Function, and Interventions

Learn more at the INSS conference website.

register

Academic Publishing 101: From Idea to Article...and Beyond

This course will be held online via Zoom. Registration is required to secure your spot. This course will NOT be recorded – attendance is required.

Although graduate school teaches you many things, many PhD students complete their dissertations having never been fully trained in academic publishing. How does academic publishing actually work? Where should you publish your research? How do you actually get papers accepted in strong academic journals? In this talk, we will discuss several major ideas in academic publishing (focusing on the social sciences). We will discuss:

• professional integrity and ethics
• the role of academic conversations and communities as a guide for publication forums and journal selections
• the mechanics of publishing in journals and other forums (including outlining, writing style, journal, legal, and newspaper submissions, the peer review process, revisions, and corresponding with editors)
• acceptance and all that follows.

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Effect of Financial Incentives and Default Options on Food Choices of Adults With Low Income in Online Retail Settings

This NIH Collaboratory Rethinking Clinical Trials Grand Rounds features:

Pasquale Rummo, PhD, MPH
Associate Professor
NYU Grossman School of Medicine

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