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Transmission electron micrograph of HIV-1 virus particles (colorized red) replicating from an HIV-infected H9 T-cell (blue). Image captured at the NIAID Integrated Research Facility (IRF) in Fort Detrick, Maryland. Credit: NIAID

New trial highlights incremental progress towards a cure for HIV-1

Antiretroviral therapies (ART) stop HIV replication in its tracks, allowing people with HIV to live relatively normal lives. However, despite these treatments, some HIV still lingers inside cells in a dormant state known as “latency.” If ART is discontinued, HIV will awaken from its dormant state, begin to replicate, and cause acquired immunodeficiency syndrome (AIDS). To create a cure, researchers have been attempting to drive HIV out of latency and target it for destruction. A new clinical trial led by clinicians and researchers at the UNC School of Medicine suggests that a combination of the drug vorinostat and immunotherapy can coax HIV-infected cells out of latency and attack them.

The immunotherapy was provided by a team at the George Washington University, who took white blood cells from the study participants and expanded them in the laboratory, augmenting the cells' ability to attack HIV-infected cells, before re-infusion at the NC TraCS Clinical and Translational Research Center (CTRC) which provided space and skilled nursing staff for the treatment and follow-up visits for the trial.


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TraCS CPAB member publishes research on how word choice affects children’s perceptions of their own health

Catalina Berenblum Tobi, member of the NC TraCS Equity in Research Community & Advisory Board publishes qualitative research outlining how metaphors used when explaining inflammatory bowel disease affect young patients’ perceptions of illness and healing.

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Addressing health equity and clinical research issues at the North Carolina coast

The Research Advisory Council is currently accepting applications for five programs. New March submission deadlines have been added for Promoting Clinical Research in Southeastern North Carolina awards and Promoting Health Equity in Southeastern North Carolina awards.

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UNC OHRE and the IRB announce office hours opportunity

The UNC Office of Human Research Ethics and the Institutional Review Board are offering office hours twice a month on Wednesdays in 15-minute blocks from 9–11 a.m., currently scheduled through June 2024. Both virtual and in-person sessions are available depending on date.

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TraCS welcomes new Community and Patient Advisory Board members

TraCS is excited to announce the addition of five new members to the Equity in Research Community and Patient Advisory Board (CPAB). The NC TraCS CPAB promotes and supports equity in research at UNC-Chapel Hill through community engagement, inclusive science, and diverse recruitment.


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Advancing the research agenda at UNC-Chapel Hill

Watch our new video and learn what’s possible with support from NC TraCS – drones that deliver life-saving equipment, potential mental health treatment based on brain wave therapy, and 3D-printed intravaginal rings to deliver therapeutics are just a few of the possibilities. We’re here to help strengthen and accelerate research at UNC-Chapel Hill and beyond.

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TraCS program works to support inclusive research and health equity

ISP works to achieve health equity among communities who are Black and Indigenous; children and adolescents; Disabled, blind, d/Deaf and hard of hearing, and/or neurodivergent; Latino/a/e/x; LGBTQIA and gender diverse; migrants and refugees; and older adults.
Community and Patient Advisory Board members

Community and Patient Advisory Board

The TraCS Community and Patient Advisory Board promotes and supports equity in research. The 11-member CPAB consists of community members, patients, and advocates with varied perspectives, backgrounds, and experiences.
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