Nonparametric Curve Estimation: Data Exploration and Inference

The NC TraCS Biostatistics Seminar Series helps clinical and translational researchers collaborate more effectively with consulting biostatisticians by building deeper understanding of key statistical concepts and methods. Researchers then are better able to (1) evaluate relevance of the concept or method for research aim(s) definition and choice of study design; and (2) properly interpret the results of data analysis.

In this seminar, J.S. Marron, PhD, will explore smoothing methods for curve estimation that can discover useful insights in contexts where there is not an obvious statistical model, and often can also indicate poorly fitting models. Methods for understanding which discovered features represent important underlying structure will also be discussed.

Marron is the Amos Hawley Distinguished Professor in UNC's Department of Statistics and Operations Research as well as a professor in the Department of Biostatistics at the UNC Gillings School of Global Public Health. He is widely recognized as a world research leader in the statistical disciplines of high dimensional, functional and object oriented data analysis, as well as data visualization. He has made broad major contributions ranging from the invention of innovative new statistical methods, through software development and on to statistical and mathematical theory. Marron's research continues with a number of ongoing deep, interdisciplinary research collaborations with colleagues in Computer Science, Genetics, Medicine, Mathematics and Biology. A special strength is his strong record of mentoring graduate students, postdocs and junior faculty, in both statistics and also related disciplinary fields.

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Big Data, Big Deal? Exploring the Potential & Peril of Modern Data Sources for Social Science Research

This 5-hour course will be offered online only. Attendance is required – this course will not be recorded.

In this workshop we will offer an overview of big data types and sources and discuss their potential for survey and social science research as well as pitfalls. Specifically we will discuss social media data, digital trace data, administrative data and sensor data through a total data quality lens. We will address quality issues with each type of data, possible error frameworks to use in working with these specific data types and discuss ways to quantity data quality through a collection of metrics. We end the workshop with a discussion of how to maximize data quality for these data sources. The workshop will include several examples of work taken from the recent survey research, social science and information systems science literature and we will also include several interactive activities aimed at reinforcing key concepts around recognizing and possibly mitigating quality issues that may arise when working with these data types for social science type research.

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Guidelines for Design and Analysis of Stepped-Wedge Trials

This NIH Collaboratory Rethinking Clinical Trials Biostatistics Series Grand Rounds features:

Speaker: James P. Hughes, PhD
Professor Emeritus of Biostatistics, University of Washington

Moderator: Patrick J. Heagerty, PhD
Professor of Biostatistics, University of Washington

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The A's, B's, and ZZZ's of Sleep in RA and Lupus

Join the UNC School of Medicine Thurston Arthritis Research Center for a UNC Core Center for Clinical Research (CCCR) Speaker Series seminar featuring Patti Katz, PhD. Katz is a Professor of Medicine and Health Policy at the University of California San Francisco.

In this talk, Katz will review what we know about sleep in both conditions and how sleep may be related to disease outcomes. She will also talk about her research in the area of sleep in RA and lupus.

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FDA Clinical Investigator Training Course

This course is designed to promote professionalism in the clinical trial industry for individuals involved with submissions to FDA (Investigational New Drug (IND) application, New Drug Application (NDA), Biologics License Application (BLA)), and to familiarize stakeholders with the regulatory and scientific issues involved in the development and approval of medical drugs and biological products.

INTENDED AUDIENCE: This is a clinical investigator training course targeted at all stakeholders in the clinical trial enterprise including industry, academia, and regulators (both local and foreign).

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NC BERD Seminar: Interaction and effect modification: what are they and how are they different

This advanced-level session will introduce, describe, and distinguish causal interaction and effect measure modification.

Presenter: Mike Bancks, PhD, MPH
Assistant Professor, Epidemiology and Prevention, Wake Forest University School of Medicine

This event is hosted by Wake Forest and being cross-promoted by the NC BERD Consortium, a collaboration of the CTSA-funded BERD cores at UNC-Chapel Hill, Wake Forest University School of Medicine, and Duke University School of Medicine.

FDA Clinical Investigator Training Course

This course is designed to promote professionalism in the clinical trial industry for individuals involved with submissions to FDA (Investigational New Drug (IND) application, New Drug Application (NDA), Biologics License Application (BLA)), and to familiarize stakeholders with the regulatory and scientific issues involved in the development and approval of medical drugs and biological products.

INTENDED AUDIENCE: This is a clinical investigator training course targeted at all stakeholders in the clinical trial enterprise including industry, academia, and regulators (both local and foreign).

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A Pragmatic Randomized Trial of the Jumpstart Intervention to Promote Communication About Goals of Care for Hospitalized Patients with Serious Illness

This NIH Collaboratory Rethinking Clinical Trials Grand Rounds features:

Ruth Engelberg, PhD
University of Washington

Erin Kross, MD
University of Washington

Robert Lee, MD, MS
University of Washington

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Community Engagement in Research at Carolina: Updates and Moving Forward

Please join the Department of Health Sciences Office of Research & Scholarship for their December research forum featuring Essie Torres, PhD, MPH, Director of Workforce Strategy and Community Partnerships in the UNC Office of the Vice Chancellor for Research.

The hybrid forum will take place in person (MacNider 321, LUNCH provided) and via Zoom. Please register to attend.

Questions? Contact the Department of Health Sciences Office of Research & Scholarship at This email address is being protected from spambots. You need JavaScript enabled to view it..

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A Lung Three Pointer: Integrin Regulation of Branching, Cilia, and the Basement Membrane

Join the Children's Research Institute and Neonatal-Perinatal Medicine for a hybrid seminar with Erin J. Plosa, MD, Assistant Professor of Pediatrics, Mildred Stahlman Division of Neonatology, Vanderbilt University Medical Center. Participate in the seminar either in person at 3116 Mary Ellen Jones Building (with lunch provided) or via Zoom.

Zoom information - Meeting ID: 985 6644 6544 | Password: 097476

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AAP-SPROUT Tele-inpatient ECHO: Teleneonatology

The American Academy of Pediatrics is recruiting hospitalists, pediatricians, and other health professionals to be a part of the SPROUT (Supporting Pediatric Research on Outcomes and Utilization of Telehealth) Tele-inpatient ECHO (Extension for Community Healthcare Outcomes). This ECHO, in partnership with the SPROUT-CTSA Network, will serve as a forum for increasing knowledge, skills, and self-efficacy regarding effective strategies and best practices related to telehealth in the hospital setting.

Project ECHO® is an innovative hub and spoke program, designed to create knowledge networks by connecting health care providers with an expert team through a tele-mentoring program using brief lectures and case‐based presentations. This ECHO, in partnership with the SPROUT-CTSA Network, will serve as a forum for increasing knowledge, skills, and self-efficacy regarding effective strategies and best practices related to telehealth in the hospital setting.

The AAP-SPROUT Tele-inpatient ECHO will meet monthly September 2023 through February 2024 at at 12 PM ET on the following dates: September 13, October 11, November 15, December 13, January 10, and February 14. Participants are eligible to claim CME/MOC 2 credits.

December 13, 2023 topic: Teleneonatology| Presenter: Jennifer Fang, MD, FAAP | Facilitator: Jordan Vaughn, MD, FAAP

Questions? Email Robinn Yu, Program Manager of ECHO Initiatives, This email address is being protected from spambots. You need JavaScript enabled to view it.

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This project was supported in part by NIH/ NCATS SPROUT-CTSA Collaborative Telehealth Network Grant Number U01TR002626. The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH.

UNC NRP December 2023 Education Session: Investigational Drug Services (IDS) Overview of Services

Please join the UNC Network for Research Professionals and Maria Bullis, PharmD, for an overview of Investigational Drug Services (IDS) services.

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Diversifying Clinical Trials: A Path Forward

This NIH Collaboratory Rethinking Clinical Trials Grand Rounds features:

Roxana Mehran, MD
Icahn School of Medicine at Mount Sinai

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