A "nurse-intensive" study is one that requires direct CTRC RN involvement at some point during the study. This generally includes visits or procedures that cannot be delegated to non-licensed staff, such as medication administration, serial blood draws from a PIV, or participant monitoring. This designation does not necessarily mean the visit is complex or high-acuity; it simply indicates that RN involvement is required.

Studies that are nurse-intensive (with some exceptions, determined based on study-specific requirements) will incur a CTRC startup fee of $1,005. This fee covers activities such as creating CTRC-specific flow sheets or orders and coordinating RN training and study logistics. The fee is invoiced once the nursing flow sheet and orders are initiated or after the Site Initiation Visit (SIV), whichever occurs first.

Investigators will be notified if a study is assessed the startup fee during the CTRC study review process. Investigators are also welcome to contact This email address is being protected from spambots. You need JavaScript enabled to view it. during budget discussions to determine whether the fee is likely to apply before the study review is completed.