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Odum Institute: Introduction to Constructivist Grounded Theory

Wed. 4 Oct, 2023 9:00 am - 11:30 am

This course will take place over three mornings (10/2/23, 10/4/23, and 10/6/23), 2.5 hours per morning, and will be offered via Zoom. Attendance is required as the course will not be recorded.

This course introduces participants to constructivist grounded theory (CGT). Grounded theory (GT) methods consist of flexible guidelines to fit particular research problems, not to apply mechanically. With these guidelines, you expedite and systematize data collection and analysis. GT methods can assist researchers in making their work more analytic, precise, and compelling.

In this course, following an exploration of the history and development of GT, we examine GT basic guidelines and major strategies, including initial line-by-line and focused coding, the use of gerunds, memoing, diagramming, theoretical sampling, and categorising. Throughout the sessions, there is an emphasis on CGT's epistemological foundation and resultant adaptations to the research process, including regarding the literature review, researcher positionality/ies and reflexivity, and participant involvement.

The course will include a number of hands-on exercises to exemplify, and give participants an opportunity to practice, the strategies being discussed. For the coding exercise, you may bring and use some of your own qualitative data, or if you do not have data yet, some will be supplied. Clear guidelines and support are provided to course participants with regard to all aspects of CGT.

The sessions will utilise CGT readings and resources from Kathy Charmaz, Robert Thornberg, Adele Clarke, and the presenter, Elaine Keane, and will draw on the extensive scholarship of Barney Glaser and Anselm Strauss. A pack of materials will be shared with participants in advance of the course. This course will be of interest to those doing full CGT studies but also to those who may be interested in learning about and potentially using some of the powerful GT strategies (such as coding) in studies with a different overall methodological approach.

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NC BERD Seminar: Statistical Power

Wed. 4 Oct, 2023 12:00 pm - 1:00 pm

NC BERD Seminar: Statistical Power: Understanding the inputs and how you come up with them

This session will cover approaches to estimate statistical power, sample size, and effect estimates to be considered in the study design phase.

Presenter: Walter Ambrosius, PhD
Professor, Biostatistics and Data Science, Wake Forest University School of Medicine

This event is hosted by Wake Forest and being cross-promoted by the NC BERD Consortium, a collaboration of the CTSA-funded BERD cores at UNC-Chapel Hill, Wake Forest University School of Medicine, and Duke University School of Medicine.

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Cystic Fibrosis: Precision Treatment of a Rare Monogenic Disease Mini-Symposium

Wed. 4 Oct, 2023 3:00 pm - 5:00 pm
PPMH symposium graphic - B/W sketch of lungs

Join the UNC Program for Precision Medicine in Health Care (PPMH) for Cystic Fibrosis: Precision Treatment of a Rare Monogenic Disease, a free virtual mini-symposium.

Cystic fibrosis (CF) is caused by two single-nucleotide changes to a single gene, the cystic fibrosis transmembrane conductance regulator (CFTR). The CFTR gene contains the instructions for making a protein that carries water and salt across cell membranes. When the CFTR gene is not working correctly, mucus can accumulate in the lungs and digestive system.

Speakers will address research into developing new CF therapies, methods for determining which therapy will most benefit individual patients with CF, and how the EHR can be leveraged to streamline treatment for patients with CF.

Presentations

Developing small-molecule therapies to rescue rare CFTR variants
Rhianna Lee, PhD
Postdoctoral associate, Duke University, Cell Biology Department

Personalized medicine, the fight against antibiotic resistance, and precision dosing
Gauri Rao, PharmD
Associate Professor, USC Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California Adjunct Associate Professor, UNC Eshelman School of Pharmacy, UNC Chapel Hill

From Data to Dosing: Streamlining CF modulator choices
Michael Adams, MD
Clinical Instructor, Division of Genetics & Metabolism, Department of Pediatrics, UNC School of Medicine

For more information, visit www.med.unc.edu/ppmh.

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