Funding Opportunity: Clinical Trials to Validate AI-Driven Drug Repurposing
Cures Within Reach (CWR) is a non-profit organization that focuses on accelerating the development of new treatments for diseases by repurposing existing drugs, devices, and other therapies. They do this by funding proof-of-concept clinical trials that test these therapies for new indications, effectively speeding up the process of finding new treatments for patients.
CWR has announced a new Request for Proposals (RFP) for Clinical Trials to Validate AI-Driven Drug Repurposing.
CWR is accepting budgets of up to $100,000 for proof of concept, Phase I or Phase IIA clinical trials that have AI-generated data as part of the preclinical support.
RFP highlights include:
- Projects must repurpose already approved drugs, biologics or eligible cellular/gene therapies, with a preference for off patent therapies
- Any unsolved disease is eligible, with a preference for rare diseases
- PIs from anywhere in the world and at any career stage can apply; there's no limit to the number of submissions from any institution or PI
- Any AI model is eligible to generate preclinical supporting data, with a preference for openly accessible models and for models developed by nonprofits/government
- CWR has created a document "Potential AI Model Resources for CWR" solely to provide options to PIs and as just one resource of potential AI models that could be used as part of an RFP submission
- Budgets of up to $100,000, including the required 10% institutional match, are accepted; additional funds are available for community engagement
View the RFP at cureswithinreach.org.
Submission Date
LOI submissions are due by August 25, 2025 on ProposalCentral using the Non-Disease Specific Repurposing Research program; top scoring LOIs will be invited to submit a full proposal.