UNC’s Drug-Discovery Center attracts $3 million gift

Originally published in UNC News

Gift will support the Center for Integrative Chemical Biology and Drug Discovery at the UNC Eshelman School of Pharmacy

(Chapel Hill, N.C. – Oct. 21, 2014) – The pharmacy school at the University of North Carolina at Chapel Hill has received a $3 million gift from philanthropist and pharmaceutical-industry executive Fred Eshelman.

Eshelman’s gift will support the work of the school’s Center for Integrative Chemical Biology and Drug Discovery. The center is dedicated to evaluating and developing potential drug targets discovered by UNC faculty.

The UNC Eshelman School of Pharmacy is one of the nation’s top pharmacy schools. It ranks second in total research funding and has the number-two doctor of pharmacy program in the nation, according to U.S. News & World Report.

The CICBDD

Researchers at UNC-Chapel Hill often discover interesting biological systems that could represent novel drug targets. These targets can be thought of as locks, and the CICBDD studies the “locks” to see if a pharmaceutical key can be created to stop or start biological processes related to diseases.

cicbdd2

Center for Integrative Chemical Biology and Drug Discovery at the UNC Eshelman School of Pharmacy

The CICBDD bridges the gap that exists between the biological sciences that define the basis for disease (the locks) and translational medicine, which creates treatments for patients (the keys). This gap exists at almost all universities and as a consequence, academic drug discovery centers are a growing enterprise, said Stephen Frye, the center’s director.

The center has a strong focus on seeking new treatments for cancer. In its seven years of existence, the center has collaborated with more than 45 research groups at UNC-Chapel Hill and brought in approximately $20.5 million in research funding. This activity has resulted in a number of filed patents and contributed to the creation of two spinoff companies.

“This gift will enable us to advance scientific discoveries made by UNC faculty by creating new medications to benefit cancer patients,” said Frye, who is also one of the pharmacy school’s Fred Eshelman Distinguished Professors. “We are very grateful to Dr. Eshelman for continuing his support of the center and of our collaborations with faculty in the Lineberger Comprehensive Cancer Center and across campus.

“Knowing he believes so strongly in our ability to develop new therapies for cancer patients is very motivating for us.”

Fred Eshelman

Eshelman graduated from the pharmacy school at UNC-Chapel HIll in 1972 and founded Wilmington-based PPD Inc. in 1985.

He has supported the school with gifts totaling approximately $38 million and serves as a member of its board of visitors and as an adjunct faculty member. In 2008, the pharmacy school at UNC-Chapel Hill was renamed in his honor.

Photos:

Stephen Frye:http://uncnews.unc.edu/files/2014/10/stephenfrye.jpg

Center for Integrative Chemical Biology and Drug Discovery: http://uncnews.unc.edu/files/2014/10/cicbdd2.jpg

UNC Eshelman School of Pharmacy contact: David Etchison, (919) 966-7744, This email address is being protected from spambots. You need JavaScript enabled to view it.

Communications and Public Affairs contact: Helen Buchanan, (919) 962-2092, This email address is being protected from spambots. You need JavaScript enabled to view it.

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