Skip to main content

Funding Opportunity: RC2 companion grant to enhance clinical and translational science

NCATS logo

NC TraCS is accepting Letters of Intent (LOIs) for a competitive internal selection process to identify a high-impact project to be developed and submitted as its next NIH RC2 Companion Grant.

This NCATS RC2 opportunity (PAR-25-156) is intended to support innovative resources, activities, and expertise that enhance clinical and translational science (CTS). Project budgets are limited to $500,000 per year in direct costs for up to 5 years ($2.5M over the 5 years of the grant). TraCS will select the most meritorious LOI and provide intensive support to develop a full RC2 application.

Briefly, the High Impact Specialized Innovations Programs (SIPs), supported through this RC2 mechanism should:

  • Address specific outcomes that promote and advance the NCATS Strategic Plan and address one or more of the CTSA Program Goals
  • Accelerate the development of innovative resources, approaches, tools, solutions, therapies, diagnostics,devices and/or applications and help overcome roadblocks in CTS
  • Help catalyze CTS locally at UM1 hubs where no other existing project/resource is likely or able to do so
  • Generate results and resources that are expected to become integrated into the broader CTS community locally, regionally, and/or nationally
  • Have a plan for evaluation and sustainability of applicable research efforts and resources beyond the RC2 funding

LOIs due: April 14, 2026 | Anticipated RC2 submission deadline: September 28, 2026

View RFA (pdf)

View news related to policies and regulations

Have news or an announcement to share? Contact Michelle Maclay at michelle_maclay@med.unc.edu

Get NC TraCS events and news delivered to your inbox! Subscribe to our weekly email blast