The four Carolinas CTSAs (Duke University, the Medical University of South Carolina, the University of North Carolina at Chapel Hill‐RTI partnership, and Wake Forest University) have partnered with the Carolinas Collaborative.
Managed by Health Sciences South Carolina (HSSC) and funded through the Duke Endowment, the Carolinas Collaborative provides a data resource (i2b2/Shrine) that harmonizes the electronic health record data elements highlighted in the CDMv3.0 across the institutions to expedite clinical research and quality improvement activities.
This pilot program is designed to encourage and facilitate novel clinical and translational research that applies or accelerates discovery into testing in clinical or population settings. The proposed pilot work should collect preliminary data to lead to a competitive proposal submitted to an external funding agency (NIH, AHRQ, PCORI, foundation, etc.) within one year from onset of funding.
Projects must demonstrate high translational potential with a clear path to subsequent grant support for a cohort study or clinical trial. Population health improvement projects should demonstrate significant stakeholder involvement to move it into broader practice patterns, clinical guidelines, and other applications.
Projects must use the component EHR data warehouses from at least two of the four CTSAs. The individual CTSAs, in collaboration with Health Sciences South Carolina (HSSC), will assist funded awardees in data harmonization activities across the multiple sites using tools including i2b2 and SHRINE.
New requirements for funded pilot grants
The NC TraCS Institute is funded through a CTSA grant from NIH's National Center for Advancing Translational Sciences (NCATS). NCATS recently instituted a new policy requiring the review and approval of all TraCS pilot grants involving human subjects research prior to TraCS funds being released. Therefore, if your proposal is funded and involves human subjects research, TraCS will require additional documentation to send to NCATS. NCATS expects to complete their review in less than 30 days. The NCATS review can occur concurrently with the IRB review; however, final NCATS approval is contingent upon IRB approval.
Submission Due Date
Spring 2017Apply Online
Learn more about current Carolinas Collaborative research projects