The new UNC Clinical Genomic Analysis (GENYSIS) core facility enables researchers to offer validated reporting of clinically relevant results to participants who have genomic sequencing as part of their IRB-approved studies.

GENYSIS offers a no-cost consultation to help PIs plan or modify a clinical genomics research study. The core welcomes established and pilot projects and can help identify internal funding opportunities for new projects.

GENYSIS services include:

• assistance with IRB applications and consent form composition
• coordination with the BioSpecimen Processing facility (BSP) for DNA extraction and storage
• coordination with the High Throughput Sequencing Facility (HTSF) for short or long read sequencing
• bioinformatics pipeline for identifying sequence and structural variants
• experienced variant analysts to review and classify clinically relevant variants
• discussion of relevant variants at a weekly interdisciplinary team meeting
• Sanger confirmation in a CAP accredited/CLIA certified lab
• a clinical laboratory report provided that can be released in Epic if the research participant is a UNC patient
• post-test services, including return of results by a genetic counselor

For more information, visit www.med.unc.edu/genysis or email This email address is being protected from spambots. You need JavaScript enabled to view it..